 |
PUBLICATIONS, SCIENCE AND RESEARCH |
|
|
 Years of experience and research have
affirmed the positive effects of BIOPTRON Light Therapy
and have led to a wide range of applications in numerous
fields of medicine. The therapy has become accepted as
a new form of treatment in prevention, therapy and rehabilitation
worldwide.
The scientific team of BIOPTRON AG is working
continuously with experts, researchers and physicians
in many countries in order to examine the characteristics
and therapeutic effectiveness of BIOPTRON Light Therapy
in many different areas.
SCIENTIFIC REFERENCE LIST
1. Finsen, R.N. Phototherapy. London: Edward Arnold, 1904
2. Mester, E., Mester, A.F., Mester, A. The biomedical
effects of laser application. Lasers Surg Med 1985; 5:
31-39
3. Fenyo, M. Theoretical and experimental basis of biostimulation.
Optics Laser Technol 1984; 16: 209-215
4. Karu, T. Molecular mechanism of therapeutic effect
of low-intensity irradiation. Laser Life Sci 1988; 2:
63-71
5. Karu, T. Primary and secondary mechanisms of action
of visible to near-IR radiation on cells. J Photochem
Photobiol 1999; 49(1): 1-17
6. Smith, K.C. The photobiological basis of low-level
laser radiation therapy. Laser Therapy 1991; 3: 19-24
7. Mester, E., Spiry, T., Szende Tota, J.G. Effects of
laser rays on wound healing. Am J Surg 1971; 122: 532-535
8. Fenyo, M., Mandl, J., Falus, A. Opposite effect of
linearly polarized light on biosynthesis of interleukin-6
in a human B lymphoid cell line and peripheral human monocytes.
Cell Biology International 2002; 26(3): 265-269
9. Medenica, L., Lens, M. The use of polarised polychromatic
non-coherent light alone as a therapy for venous leg ulceration.
Journal of Wound Care 2003; 12(1): 37-40
10. Lordanou, P., Baltopoulos, G., Giannakopoulou, M.,
Bellou, P., Ktenas, E. Effect of polarized light in the
healing process of pressure ulcers. Int J
Nurs Pract 2002; 8(1): 49-55
11. Monstrey, S., Hoeksema, H., Saelens, H., Depuydt,
K., Hamdi, M., Van Landuyt, K., Blondeel, P. A conservative
approach for deep dermal burn wounds using polarised-light
therapy. British Journal of Plastic Surgery 2002; 55:
420-426
12. Bjordal, J.M., Couppe, R.C., Chow, R.T., Tuner, J.,
Ljunggren, E.A. A systematic review of low-level laser
therapy with location-specific doses for pain from chronic
joint disorders. Aust J Physiother 2003; 49(2): 107-116
13. Marks, R., de Palma, F. Clinical efficacy of low-power
laser therapy in osteoarthritis. Physiother Res Int 1999;
4(2): 141-157
14. Ozdemir, F., Birtane, M., Kokino, S. The clinical
efficacy of low-power laser therapy on pain and function
in cervical osteoarthritis. Clin Rheumatol 2001; 20(3):
181-184
15. Gur, A., Karakoc, M., Cevik, R., Nas, K., Sarac, A.J.,
Karakoc, M. Efficacy of low-power laser therapy and exercise
on pain and functions in chronic lower back pain. Lasers
Surg Med 2003; 32(3): 233-238
16. Gur, A., Karakoc, M., Nas, K., Cevik, R., Sarac, J.,
Demir, E. Efficacy of low-power laser therapy in fibromyalgia:
a single-blind, placebo-controlled trial. Lasers Med Sci
2002; 17(1): 57-61
17. Simunovic, Z., Ivankovich, A.D., Depolo, A. Wound
healing of animal and human body sport and traffic accident
injuries using low-level laser therapy treatment: a randomized
clinical study of seventy-four patients with control group.
J Clin Laser Med Surg 2000; 18(2): 67-73
18. Tam, G. Low-power laser therapy and analgesic action.
J Clin Laser Med Surg 1999; 17(1); 29-33
19. Minor, M.A., Sanford, M.K. The role of physical therapy
and physical modalities in pain management. Rheum Dis
Clin North Am 1999; 25(1); 233-248
20. Fulga, C. Anti-inflammatory effect of laser therapy
in rheumatoid arthritis. Rom J Intern Med 1998; 36(3-4):
273-279
21. Dinshah, D. Let there be light. NJ USA, ISBN 0-933917-00-7
A BRIEF SUMMARY OF SOME MEDICAL PUBLICATIONS AND SCIENTIFIC RESEARCH
• THE USE OF POLYCHROMATIC POLARISED LIGHT BIOPTRON
IN PHYSIOTHERAPY
Polychromatic, polarised light therapy compared with SHORT
WAVE DIATHERMY. Humeroscapular periarthritis, trigeminal
neuralgia, neuralgia of the intercostals nerves, tendovaginitis
antebrachi, etc. Pain control using light therapy. Full report available on request to medical professionals and therapists.
Source : ACADEMY OF MILITARY MEDICINE. CLINIC for PHYSICAL
MEDICINE and REHABILITATION. DR M. ANTONIC. SEPT 1990.
BELGRADE, YUGOSLAVIA.
• AVOIDING SURGERY IN THE TREATMENT OF DEEP
DERMAL BURN WOUNDS USING POLARISED LIGHT
“The results of this study demonstrate that polarised
light is very useful in the treatment of deep dermal burn
wounds. It accelerates woundhealing and at the same time
produces less hypertrophic scars. The results of this
study clearly demonstrate that polarised light therapy
seems to be a valuable alternative for the operative treatment
of deep dermal burn wounds, with even better aesthetic
and functional results”. Full report available on request to medical professionals and therapists.
Source : BRITISH JOURNAL OF PLASTIC SURGERY, APRIL 2002.
Stan Monstrey, MD, PhD, FCCP, Koen Van Landuyt, MD, FCCP,
Koen Depuydt, MD, Phillip Blondeel, MD, PhD, Henk Hoeksema.
• THE USE OF POLARISED POLYCHROMATIC NON-COHERENT
LIGHT ALONE AS A THERAPY FOR VENOUS LEG ULCERATION
“Phototherapy treatments were given once a day for
8 minutes during 4 weeks. All ulcers except one (99%)
had a positive value for the change in healing area at
the end of 4 weeks. Mean overall healing rate was 3.53
sq cm per week. No adverse side effects were observed.
Polarised, polychromatic light therapy applied as a monotherapy
was associated with positive healing rates in patients
with venous leg ulcers. It is a simple and non-invasive
treatment…”. Full report available on request to medical professionals and therapists.
Source : JOURNAL OF WOUND CARE, VOL 12, No 1, JANUARY 2003.
M. LENS, MD, PhD - UNIVERSITY OF OXFORD, L. MEDENICA,
MD - UNIVERSITY OF BELGRADE.
• OPPOSITE EFFECT OF LINEARLY POLARISED LIGHT
ON BIOSYNTHESIS OF INTERLEUKIN-6 IN A HUMAN LYMPHOID
CELL LINE AND PERIPHERAL HUMAN MONOCYTES
The effects of linearly polarised light and diffuse light
on the in vitro interleukin-6 (IL-6) production in a human
B Lymphoma cell line (BMNH) and peripheral monocytes of
healthy volunteers are compared. Full report available on request to medical professionals and therapists.
Source : CELL BIOLOGY INTERNATIONAL. 2002. VOL 26, no 3.
M. FENYO, J. MANDL, A. FALUS - DEPT OF MEDICAL CHEMISTRY,
MOLECULAR BIOLOGY AND PATHOBIOCHEMISTRY, SEMMELWEIS MEDICAL
UNIVERSITY.
• PROMOTION OF WOUND HEALING BY IRRADIATION
WITH POLARISED LIGHT
“Clinical experience is
reported in the treatment of intransigent wounds with
polarised light of defined energy content.. Acceleration
of granulation formation and epithelialisation , and reduction
of both wound secretion and wound pain were observed”
Main indications for application discussed. Full report available on request to medical professionals and therapists.
Source : DIE MEDIZINISCHE WELT, 1986. VOL 37. DR A.D. STACKER
- HEAD OF SURGICAL DEPT, ST JOSEPH HOSPITAL, BREMERHAVEN,
GERMANY.
• THE EFFECT OF POLARISED LIGHT ON WOUND HEALING
“The results of this study demonstrated
that polarised light had a beneficial effect on the healing
of these standardised wounds, resulting in a faster epithelialisation
and an improved quality of early scar tissue formation”. Full report available on request to medical professionals and therapists.
Source : EUROPEAN JOURNAL OF PLASTIC SURGERY. ACCEPTED
FOR PUBLICATION 27 NOV, 2000. PUBLISHED ONLINE. HOEKSEMA,
DEPUYDT, VAN MAELE, VAN LANDYT, BLONDEEL - DEPT OF PLASTIC
SURGERY, UNIVERSITY HOSPITAL, GENT, BELGIUM.
• SINGLE SKIN EXPOSURE TO VISIBLE POLARISED
LIGHT INDUCES RAPID MODIFICATION OF ENTIRE CIRCULATING
BLOOD
1. IMPROVEMENT OF RHEOLOGIC AND IMMUNE PARAMETERS.
“We have
found that exposure of a small skin area of healthy volunteers
to visible incoherent polarised (VIP) light in therapeutic
doses induces a rapid structural-functional modification
of erythrocytes, leukocytes, and some plasma components
in the whole circulating volume of blood……”. Full report available on request to medical professionals and therapists.
Source : PROGRESS IN BIO MEDICAL OPTICS. SEPT 1988. PUBLISHED
BY THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING.
SAMOILOVA, OBOLENSKAYA, VOLOGDINA, SNOPOV & SHEVCHENKO
- INSTITUTE OF CYTOLOGY, RUSSIAN ACADEMY OF SCIENCES.
• THE EFFECT OF POLARISED LIGHT ON THE RELEASE OF
GROWTH FACTORS FROM THE U-937 MACROPHAGE-LIKE CELL LINE
“The results obtained suggests that the exposure
of U-937 cells to polarised light is followed by the release
of substances…. that stimulate the proliferative
activity of fibroblasts”. Full report available on request to medical professionals and therapists.
Source : RESEARCH REPORT - GUY’S HOSPITAL, LONDON,
UK. TISSUE REPAIR RESEARCH UNIT, DIVISION OF ANATOMY &
CELL BIOLOGY. BOLTON, DYSON, AND YOUNG, 1992.
• EFFECT OF POLARISED LIGHT IN THE HEALING PROCESS
OF PRESSURE ULCERS
“This trial demonstrated the effectiveness
of polarised light therapy in healing 1st, 2nd and 3rd
grade pressure ulcers. When polarised light treatment
was added to conventional ulcer therapy, rapid changes
in appearance and size with complete healing in half of
the cases and accelerated partial healing in the remaining
cases appeared within 1 - 2 weeks”. Full report available on request to medical professionals and therapists.
Source : INTERNATIONAL JOURNAL OF NURSING PRACTICE. 2002.
VOL 8, 49-55. PANGIOTA IORDANOU RN, PGDHHSA, ANA, BsC
(Nurs), PhD. G BALTOPOULOS - PROFESSOR OF CRITICAL CARE
ATHENS UNIVERSITY SCHOOL OF NURSING, M. GIANNAKOPOULOU
BsC (Nurs), PhD - ATHENS UNIVERSITY.
• EFFECT OF VISIBLE LIGHT ON SOME CELLULAR AND
IMMUNE PARAMETERS
“ …. visible light provokes the release of
some biological mediators (cytokines) from the immune
competent cells and in this way stimulates the natural
resistance of an organism. Similar to UV radiation and
without the negative effect of suppressed natural killer
cell activity, the application of visible light, preferably
linearly polarised light (LPL), for the extracorporeal
exposure of human blood is suggested”. Full report available on request to medical professionals and therapists.
Source : JOURNAL OF IMMUNOLOGY & CELL BIOLOGY. 1995.
VOL 73, 239 - 244. KUBASOVA, HORVATH, KOCSIS, and MARTA
FENYO. FREDERIC JOLIOT-CURIE NATIONAL RESEARCH INSTITUTE
FOR RADIOBIOLOGY AND RADIOHYGIENE, BUDAPEST, HUNGARY.
• HYPOTHETICAL PHYSICAL MODEL FOR LASER BIOSTIMULATION
“Polarised light reorders the polar heads of the
lipid bilayer in the cell membrane, the lipid bilayer
being near phase transition. This change in the quality
of the cell membrane influences all the processes closely
connected with it. These process modifications may yield
an explanation for biostimulation”. Full report available on request to medical professionals and therapists.
Source : OPTICS AND LASER TECHNOLOGY. FEBRUARY 1982. KERTESZ,
FENYO, MESTER & BATHORY.
• INVESTIGATIONS ON BIOLOGICAL EFFECT OF POLARIZED
LIGHT
“….the
favourable healing effects induced by polarised light
and experienced in the clinical practice (surgery, rheumatology)
were attributable primarily to the changes in the cell
membrane”. Full report available on request to medical professionals and therapists.
Source : JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY. 1988.
VOL 48, no 4. KUBASOVA, FENYO, SOMOSY & GAZSO - FREDERIC
JOLIOT-CURIE NATIONAL RESEARCH INSTITUTE FOR RADIOBIOLOGIE
AND RADIOHYGIENE, BUDAPEST, HUNGARY.
• VISIBLE LIGHT INDUCED CHANGES IN THE IMMUNE
RESPONSE THROUGH AN EYE-BRAIN MECHANISM (PHOTONEUROIMMUNOLOGY)
This publication discusses biological changes induced
by exposure to visible light through the eyes, reviews
progress in the field of photoneuroimmunology and explores
possible areas of future research. Full report available on request to medical professionals and therapists.
Source : JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY. 1995.
VOL 29, 3-15. JOAN E. ROBERTS - FORDHAM UNIVERSITY, NEW
YORK, U.S.A.
• TREATMENT OF LEG ULCERS WITH POLARISED LIGHT
Reports on the positive effects experienced in wound healing
with polarised light. Full report available on request to medical professionals and therapists.
Source : PHLEBOLOGIE UND PROKTOLOGIE. 1985. VOL 14, 96-97.
DR W. STEGMAN - SENIOR PHYSICIAN AND MEDICAL DIRECTOR
HEILANSTALT FUR BEINLEIDEN OF THE LANDESVERSICHERUNGSANSTALT,
HAMBURG, GERMANY.
• MYOFIBROTIC PAIN AND ITS THERAPY BY EVOLITE (BIOPTRON)
Extensive reports on the efficacy of VIP light therapy
on soft tissue pain syndromes, myofibrosis, general physiotherapy. Full report available on request to medical professionals and therapists.
Source : RESEARCH INSTITUTE OF THE HUNGARIAN COLLEGE FOR
PHYSICAL EDUCATION. DR PETER APOR, MARTHA FENYO, GYOZO
FEKETE.
• BIOPTRON LIGHT THERAPY AND THORACOPHRENOLAPAROTOMY
WOUND HEALING IN PATIENTS OPERATED DUE TO CARDIAC CARCINOMA
CONCLUSION: “...we found that the application of
BIOPTRON PILER therapy significantly decreases the possibility
of seroma or infection of the wound. No side effects of
this therapy have been noticed. Application of this type
of wound therapy significantly shortens the postoperative
hospitalisation. Finally, we can conclude that PILER (BIOPTRON)
light therapy should be added to the standard treatment
of all surgical wounds in patients operated due to cardiac
carcinoma. Also, we can conclude, that since we treated
one of the most demanding groups of surgical patients,
that since our results indicate excellent results, PILER
(BIOPTRON) light therapy could be successfully used in
almost all kinds of surgical wounds”. Full report available on request to medical professionals and therapists.
Source : 4TH INTERNATIONAL GASTRIC CANCER CONGRESS, NEW
YORK. APRIL/MAY 2001. PRESENTATION BY SIMIC, PESCO, BJELOVIC
& STOJAKOV - DEPT OF ESOPHAGOGASTRIC SURGERY, FIRST
SURGICAL UNIVERSITY HOSPITAL.
• AVOIDING SURGERY IN THE TREATMENT OF DEEP
DERMAL BURN WOUNDS USING POLARISED LIGHT
“Polarised light accelerates woundhealing
and at the same time results in less hypertrophic scarring.
Moreover, in many cases, no scarring was noted. Our results
clearly demonstrate that phototherapy is a valuable alternative
for the surgical treatment of deep dermal burn wounds.
Using polarised light in the treatment of 3rd degree burns
is not advisable, and absolutely no alternative for surgery”. Full report available on request to medical professionals and therapists.
Source : DEPT OF PLASTIC SURGERY, UNIVERSITY HOSPITAL,
GENT, BELGIUM. PRESENTED AT THE 10th ANNUAL MEETING OF
THE EUROPEAN ASSOCIATION OF PLASTIC SURGEONS, MADRID,
SPAIN, MAY 21, 1999. DEPUYDT, HOEKSEMA, MONSTREY, VAN
LANDUYT, BLONDEEL.
• CASE STUDIES AND CLINICAL REPORTS ON THE USE OF
BIOPTRON (VIP) LIGHT THERAPY IN RHEUMATOLOGY
Clinical assessment of the efficacy of VIP light therapy
in rheumatology - epicondylalgia, carpal tunnel syndrome,
synovitis, arthritis of the thumb, angiitis in RA, raynaud’s
disease, arthritis in the knee, cervical pain, cervicobrachial
neuralgia, cervical syndrome, rachialgia, osphyalgia,
ischialgia, rheumatoid arthritis (RA). Full report available on request to medical professionals and therapists.
Source : RHEUMATOLOGY AND REHABILITATION CENTRE - IOANNIS
STASINOPOULOS - DIRECTOR, SPECIALISED RHEUMATOLOGIST.
• IMMEDIATE AND DELAYED CHANGES IN ACTIVITY
OF LEUKOCYTES IN THE ENTIRE BLOOD CIRCULATION AS A TRIGGER
MECHANISM OF SYSTEMIC IMMUNOMODULATION FOLLOWING THE
EXPOSURE OF SKIN TO VISIBLE POLARISED LIGHT
Exposure of skin surface to VIP light at therapeutic doses
is accompanied by immediate increase in phagocytosis of
circulating monocytes and neutrophils, by stimulation
of NK-cell cytotoxic activity in respect to human malignant
K-562 cells, and by accumulation of granulocytes of bactericidal
cationic proteins…. Full report available on request to medical professionals and therapists.
Source : RESEARCH ARTICLE - INSTITUTE OF CYTOLOGY OF THE
RUSSIAN ACADEMY OF SCIENCES. OBOLENSKAYA, SAMOILOVA &
SNOPOV. |
|
|
